Summary 2012

The objectives of this workshop series are (1) to review QSAR screening methods for grouping chemicals based on their potential to induce carcinogenesis through genotoxic and epigenetic pathways, and (2) to evaluate the combined use of structural domains and in vitro data to reduce the need for the rodent carcinogen assay. The 1st McKim Workshop focused on genotoxic carcinogens, and on the potential for the cell transformation assay to identify epigenetic carcinogens. This 2nd workshop will further explore key events in epigenetic pathways as well as discuss the structural attributes for chemicals that impact those pathways.