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June 26, 2006 Registration | |
| 6:00 PM | Registration - Fitger's Inn (600 East Superior Street) |
| 7:00 PM | Social - Fireside Room at Fitger's Inn |
June 27, 2006 General Plenary Session (Open to the Public) |
|
| 9:00 AM | Celebration of Jim McKim's Career Welcome - Carl Richards, Director (EPA Mid-Continent Ecology Division) |
| 9:10 AM | Understanding the "Why" in Effects Research (A Synopsis of Jim's Accomplishments) - Gilman Veith |
| 9:40 AM | A Son's Perspective James McKim, Jr. and Michael McKim |
| 10:30 AM | Coffee Break | 11:00 AM | Plumbing 101 for Rat and Fish Models Mel Andersen |
| 11:20 AM | The McKim Approach to Measuring and Modeling Metabolism Greg Lien, Rick Kolanczyk |
| 11:40 AM | Comments from other colleagues |
| 12:00 AM | Lunch |
Risk Assessment 2026 | |
| 1:00 PM | The Paradigm Shift in Risk Assessment Steve Bradbury, Kees van Leeuwen |
| 1:40 PM | Water Quality Criteria: Implications for Testing Russell Erickson |
| 2:00 PM | Toxicity Pathways to Assessment Endpoints Pat Schmieder |
| 2:30 PM | Intrinsic Toxicity and Molecular Initiating Events Gilman Veith |
| 2:45 PM | Coffee Break |
| 3:15 PM | The Big Questions for Endocrine Disruption John Sumpter |
| 3:45 PM | A Systems-Based Approach for the Identification of Toxicity Pathways
Associated with the HPG axis Gary Ankley |
| 4:15 PM | Designing a QSAR Model for ER binding Pat Schmieder |
| 4:45 PM | A Systems Approach to Characterizing and Predicting Thyroid Toxicity Sig Degitz, Joe Tietge |
| 5:15 PM | Adjourn |
| 6:00 PM | Dinner Cruise on the Vista Queen |
June 28, 2006 Chemical Extrapolations - QSAR |
|
| 9:00 AM | Report from the Knoxville Reactive Toxicity Workshop Terry Schultz, Kendall Wallace |
| 9:40 AM | Narcosis and Baseline Toxicity Larry Brooke, Chihae Yang |
| 10:15 AM | Coffee Break |
| 10:45 AM | ECOTOX: A Foundation for Extrapolation Chris Russom |
| 11:30 AM | Read-a-Cross Methods Joop Hermens |
| 12:00 AM | Lunch |
Species-Species Extrapolations |
|
| 1:00 PM | Dose-Extrapolation Models Mel Andersen, Greg Lien |
| 1:45 PM | Metabolism in Bioaccumulation Models John Nichols |
| 2:30 PM | Species Extrapolation with PBPK Models Krishnan Kannan |
| 3:00 PM | Coffee Break |
| 3:30 PM | Predicting Metabolites and Metabolic Activation Saby Dimitrov |
| 4:00 PM | Measuring Metabolic Pathways and Activation Rick Kolanczyk |
| 4:30 PM | Inhalation Toxicity in Fish and Rodents Gilman Veith, Kendall Wallace |
| 5:00 PM | Adjourn |
| 7:00 PM | Dinner in Small Groups |
June 29, 2006 Hazard Identification |
|
| 9:30 AM | Exposure Assesment in invitro Assays Joop Hermens |
| 10:00 AM | Hazard Identification using QSAR Libraries Albert Leo, David Hoekman |