- original (ppt or pptx) presentations with recorded narration     - (ppt or pptx) slides only     - (pdf) handouts (two slides per page) REACH, risk assessment and the need for a change in mind set Kees van Leeuwen   A Framework for Building Toxicity Pathways to Complex Endpoints Gilman Veith Status of the Glutathione Reactivity Database for Skin Sensitisation Terry Schultz Estimating Human Health Endpoints with the QSAR Application Toolbox Ovanes Mekenyan Progress Report from the IQF Consortium for Skin Sensitization Models Mike Comber A Visualization Tool for Integrating Complex Toxicity Pathways Hristo Aladjov Predicting In Vivo Toxicity from In Vitro Data James McKim IV   Overview of Mitochondrial Bioenergetics & Molecular Biology Kendall Wallace   Clinical Phenotype of Mitochondrial Disease Charles Hoppel   QSAR Features for Inhibitors of Mitochondrial Bioenergetics Anatoly Starkov   Mechanisms of Mitochondrial-Mediated Cell Injury Peter O’Brien Metabolomic & Molecular Markers of Mitochondrial Toxicity Kendall Wallace   A Review of QSAR Models for Mitochondrial Effects in BioLoom Albert Leo Discussion of Chemical Targets in Mitochondria Gilman Veith Delineating Toxicity Pathways for ER Mediated Effects Patricia Schmieder   Focusing on the Adverse Outcomes of ER-mediated Pathways Rodney Johnson   Delineating Thyroid-Mediated Toxicity Pathways Michael Hornung   Thyroid-mediated CNS Dysfunction Kevin Crofton Thyroid Discussion Discussion Delineating Toxicity Pathways of Peripheral Neuropathy David Herr Inhibition and Morphogenic Pathways Involving AChE Steve Brimijoin Toxicity Pathways Mediated by Ion Channels Philip Bushnell Stress Pathways Steve Simmons