Understanding the "Why" in Effects Research Gilman Veith   Plumbing 101 for Rat and Fish Models Melvin Andersen   Species Extrapolation with PBPK Models Krishnan Kannan   New Insecticide Modes of Action Joel Coats   The Paradigm Shift in Risk Assessment Steve Bradbury, Kees van Leeuwen   A New Toxicology Testing Paradigm - Meeting Common Needs. Steve Bradbury   Water Quality Criteria: Implications for Testing Russell Erickson   Toxicity Pathways to Assessment Endpoints Pat Schmieder   The Big Questions for Endocrine Disruption John Sumpter   A Systems-Based Approach for the Identification of Toxicity Pathways Associated with the HPG axis Gary Ankley   Designing a QSAR Model for ER binding Pat Schmieder   A Systems Approach to Characterizing and Predicting Thyroid Toxicity Michael Horninig   Narcosis and Baseline Toxicity Larry Brooke, Chihae Yang   Report from the Knoxville Reactive Toxicity Workshop Terry Schultz, Kendall Wallace   ECOTOX: A Foundation for Extrapolation Chris Russom   Forming Chemical Categories Grace Patlewicz   Predicting Metabolites and Metabolic Activation Saby Dimitrov   Dosimetry in Risk Assessment and a bit More Mel Andersen, Greg Lien   Dose Extrapolation Models Greg Lein   Measuring Metabolic Pathways and Activation Rick Kolanczyk, Greg Lein   Metabolism in Bioaccumulation Models John Nichols   Inhalation Toxicity in Fish and Rodents Gilman Veith, Kendall Wallace   Read-a-Cross Methods Joop Hermens   Using 'LATENT' Information In Hazard Identification Albert Leo